Skip to main content

Chinese researchers await permission clinical trials pig organs into humans

Chinese scientists say getting closer to stepping into the pilot stage of organ transplantation of pigs as donors to humans. Researchers are waiting for the government to approve clinical trials using genetically modified pig organs for human transplants projected for the first time in 2019.

Tinuku Chinese researchers await permission clinical trials pig organs into humans

Recent experiments on monkeys showed they lived many years after receiving pig organ transplant. China is the country that has the largest pig cloning farm in the world and has an expanded supply of animals specifically for transplant heart, liver and other organs to humans.

Demand for transplant surgery in the country is also very large given the high cardiovascular disease, lung cancer and hepatitis resulting in organ failure. They are now hoping for the government to immediately grant a clinical trial permit.

"We have patients who die from organ failure and families who are desperate about the opportunity to live," Zhao Zijian, director of the Metabolic Disease Research Center at Nanjing Medical University in Jiangsu.

"The government has been silent, we understand they must be hard to make a decision, but it's time we have to get an answer," Zijian said.

By 2015 the Chinese government ceases the practice of obtaining organs from executed prisoners and raises concerns about whether enough donors will be available to meet the needs of transplants in the world's most populous country.

More than 10,000 Chinese people donate their organs during the period 2010 to 2016, but more than 1.5 million patients require transplants every year. The proposed clinical trial is part of a national xenotransplant project involving more than 10 research institutions and is funded by the central government.

Pig organs are considered the best animal candidate for human transplants because they are most similar to size and metabolism. In recent years, researchers from around the world have made breakthroughs using pig organs for xenotransplantation.

The experiments involved the lungs, kidneys and heart. Pig corneal transplants have been conducted in China since 2010 and more than 100 patients have vision recovery after surgery costs around 30,000 yuan (US$4,500).

Recent advances in biotechnology especially the CRISPR/Cas9 genome editing tools allow scientists to alter or bypass certain genes. The technique also allows scientists to modify pigs genetically to prevent the human immune system from rejecting organs after transplant surgery.

"One must take the first step, whether it's the Food and Drug Administration or the China Food and Drug Administration," Zhao said.


Popular posts

China's new energy vehicle market continues strong

Tinuku - China's new energy vehicle (NEV) sector continues to experience a major expansion in sales and production in the first half of 2018. The China Association of Automobile Manufacturers (CAAM) showed Wednesday that NEV sales increased 111.5 percent year-on-year to 412,000 units in the first six months and production rose 94.9 percent to 413,000 units.

China became the largest NEV market in the world for three consecutive years as it intensified efforts to encourage the use of NEVs to reduce environmental stress by offering tax exemptions and discounts on car purchases.

The government expects annual NEV output to reach 2 million by 2020 and NEV sales to make up 20 percent of the overall car market by 2025. CAAM reported at least 14.07 million vehicles sold in China in H1 or up 5.57 percent year on year.

The report also showed about 14.06 million vehicles were produced or up 4.15 percent and passenger car sales reached 11.78 million units with commercial vehicles of 2.29 milli…

European Union and ASEAN to restart Free Trade Agreement

Tinuku - European Union (EU) and ASEAN have agreed to restart the process of forming Free Trade Agreement (FTA). Singapore Prime Minister Lee Hsien Loong as ASEAN coordinator for EU-ASEAN relations said on Saturday to build a framework to identify potential sectors to finalize the deal.

Lee also said the EU and ASEAN had agreed to restart the process of establishing a free trade agreement between the two blocs. The EU and ASEAN launched talks towards a pact in 2007 but ignored the process two years later as the EU voted to negotiate bilaterally with each country.

"As coordinators, we look forward to forming a framework to identify where areas where we have the potential to make a deal," Lee said.

"Working on a deal may take longer than the end of the year. But if we can identify where the big opportunities are, our trade-offs, then I hope we will have better success," Lee said.

"One of the things we expect is that European nations are able to manage their soci…

Malaysia reviews potential of monopoly by Grab and Uber mergers

Tinuku - Malaysia's transport ministry said Wednesday it is studying the potential of monopoly in the ride-hailing market triggered by Grab and Uber mergers under several existing regulations. Uber Technologies Inc. sold their business in Southeast Asia to Grab in March in exchange for shares in a Singapore-based company.

The ministry said the land transport agency received many complaints about Grab raising tariffs since the merger. Grab has become the dominant player in the region. Last week, Singapore's anti-trust agency proposed a fine on Grab and Uber where mergers have reduced competition and suggested improvements such as the sale of a car rental business.

"What's imposed on taxi drivers will also be imposed on e-hailing drivers to get the driver's card. We know this is not a move that will please all parties, but we take a more balanced approach and create competition," said Transport Minister Anthony Loke

The monopoly review will be conducted by Mala…

Xiaomi makes boost in Indonesia to dominate Southeast Asian

Tinuku - Xiaomi Corporation plans to make a boost in the Southeast Asian market by opening 40 official outlets in Indonesia until the end of 2018 as the most important country in the region after being officially listed on the Hong Kong stock exchange. Manager of Xiaomi Indonesia, Steven Shi, said on Thursday the company will continue to record the company's glorious record.

The new giant smartphone maker based in Beijing is planning to open 40 official stores called Mi Store and maximize 50 service centers spread across Indonesia until the end of 2018 as a key country to continue to dominate the mobile phone market in Southeast Asia.

Xiaomi will also optimize Mi Credit and Mi Roaming recently launched. The company will do more activities aimed at strengthening relationships with Xiaomi users called Mi Fans including Mi Pop titles that have taken place in several cities in Indonesia.

Xiaomi is one of the fastest technology companies that earned a profit of CN¥100 billion in the fi…